So you Think you Know how your Database Runs?

Frances Brodsky: So you think you know all about clathrin?

M ention clathrin and what fi rst comes to mind is probably the protein's famous role in designating and constructing endocytic sites at the plasma membrane. But clathrin is a startlingly versatile protein that comes in different forms. Clathrins keep cropping up in new contexts, including actin polym-erization, mitosis, and even diabetes. Frances Brodsky has spent much of her career exploring ...

So how do you know you have a macromolecular complex?

Protein in crystal form is at an extremely high concentration and yet retains the complex secondary structure that defines an active protein. The protein crystal itself is made up of a repeating lattice of protein-protein and protein-solvent interactions. The problem that confronts any crystallographer is to identify those interactions that represent physiological interactions and those that do...

So you think you are a professional ?

The human ego provides continuous opportunities to explore the richness and variety of human perception. It is capable of excruciating truth and insight as well as delusions of grandeur that obscure truth and reality. The maturity of an individual can be defined in relation to his ability to differentiate between these extremes. The computing practitioner, being human, is no exception. His exis...

So you think you can edit?

This article presents one scientist's perspective on the transition from life at the bench to an editorial career.

So you think you can't dance?